Is it difficult? Yes, it can be. You have to be very careful when putting the male and female together. The male can get rough and kill the female so you have to watch them, not just put them together and go to work and them come home and take them out.
When do I place the female in with the male? You need to make sure that both of the fish are ready for breeding. The male will build a bubble nest (which yours already is) and the female will have vertical lines on her body. You can encourage this by putting the female into the male's tank (which you want to do cause the male needs to be comfortable with the surroundings) inside a net or container. Let her stay there for a few days. Feeding live food also helps.
How do I know there are eggs in the bubble nest? There really is no need to worry for this. The female will drop the eggs and the male will fertilize them and put them into the nest. They are usually really good at getting all of them. I do; however, reccomend using a bare bottom tank.
Who takes care of the eggs so I know who to remove if needed? As soon as the female is done laying eggs she needs to be removed. The male will take care of the eggs/babies for 2-3 days. After this time he should be removed from the tank and put into another tank. He will start eating the babies if you dont. And it is easier to remove him verse the fry.
How long does it take for the fry to hatch?usually within 24 to 36 hours.
http://majesticbettas.com/breeding.htm
I hope that this helps you out some. I did most of this info from my head so it might be a little different than the website. I did find many website if you search (I used Yahoo) for breeding Bettas.