Genetically there is definately a chance that fish have certain deformities from the get-go. Any breeder could tell you that. But fry growth is also determined by the water quality and nutrition just as the growth of any animal (humans included) is. I too used to raise platy/swordtail/molly fry and what I discovered is the higher the density of fish I had in the tank (ie crammed to the gills with fry) the smaller the fish would be at maturity. This is an adaptation of population pressure, but nothing to do with the orginal genetics of the fish.
In the wild of course, any fish with a deformity is immedately gobbled up. In domestication, fish with deformities are usually culled so they don't pass the deformity on and weaken the strain. 95% of the time fry with any type of deformity will just not thrive anyway so culling becomes a moot point.
Water quality is also very essential to fish health. The fish may be genetically perfect, but if its environment is not, then imbalances in the body could happen. Fish -are- their water quality/chemistry so if it is not proper for that fish or the fish has been improperly acclimated, then the fish will certainly suffer some ill-effect from it.
Polyautosomy human fetus usually spontaneously abort before ever being born since lots of polychromy combinations are lethal-gene combinations. The genetics book says one of the few exceptions is Down Syndrome, which is trisomy (three) #21 from incomplete seperation of the chromosome durig meiosis, and normally occures in the egg. I'd go into the whole physiological theory as to why but that would probably bore people. It is really fascinating though.
More fascinating are the sex-lined genetic abormalities such as trisomy-X, or XXY syndromes. These are mostly non-fatal.
Fish eggs that are somehow genetically defored probably just don't hatch.
~~Colesea