I have two magnum 350's and a Hot magnum. SImple and easy to maintain.
Mechanical and biological is what I use them for..no chemical is needed. You need to find some bio-max or bio-chem stars or similar media, and stick it in the carbon container(don't use the carbon except for taking out meds) That will be all you need unless you are very overstocked, or have lots of poopers for fish, then a bio-wheel may be needed(or a second filter)