If you are getting more than one, you want only one male. They are related to bettas so more than one male will fight (unless it is a REALLY big tank). With pearl gouramis, the male will develop a red chest and longer fins. The female will have a more rounded dorsal fin, and no red on the chest. They do fine by themselves too, so you don't need two unless you want two.
If you have a quarantine tank, it's always a good idea to use it. I haven't had problems with gouramis bringing stuff into the tank, and I never quarantine. Pearls aren't that sensitive or prone to diseases, so you should be fine without quarantine if you don't have a tank set up for it.