Gourami With Dropsy/ Tank Question

#1
I think one of my gouramis might have Dropsy. I've already isolated her, my questions is not about her though. I have a 56 gallon tank with one more gourami and three angelfish what can I do for them to keep them from getting sick too? It's time for their 25% water change today which I plan to do but what else can be done? Dose the tank with Melafix?