well,i'm treating my 84 gallon south american community tank.plecos,corys,brochis,a ram some neons and guppys.i used 7 out of 8 of the tablets,so i didn't treat the tanks at full strengh,just under.about one day after treatment,the neons lost the bulge in their stomachs and the corys started shoaling again.i started treating the tank because i could starve the fish and they would lose no visible girth,and my corys kept flicking off the gravel.that and growth had seemed to have been stunted in my tank.so far so good,with the treatment,i haven't even lost any of my guppy fry and none of my cats are doing paniced attempts at escape.so it seems they don't mind the meds too much.