Plexiglass is available at most larger retail hardware stores and they usually cut it to your dimensions so you shouldn't have to buy a full sheet.
Two options for installing it;
1) cut exactly to the size you want and then secure it with silicone (troublesome and messy).
2) Cut it about 3/8" wider than you need and let it hold itself in place by tension created when it bows.
If you use plexiglass, make sure you vent it. That is, use an awl or nail heated with a household propane torch to melt holes through it about two-inches apart and no closer than 1 inch to any edge. Don't try drilling plexiglass, it'll break.