Like said above you need to take care of the cause, BUT if it really gets out of control you can use Chemiclean Red Slime Remover. Just make sure you follow the instructions to a "T". I have used it in my 125 reef tank and it worked like a charm. It did come back after about a month, but not near as bad and at that point I was doing much better with my water changes and reducing feedings. Oh, and turn off your skimmer, it will drive it nuts. I waited 48 hours and two water changes later before turning it back on, and even then it will take a few hours to get back to normal. Again, it won't take away the cause of your Red Slime, but it will get rid of it fast.