There is always some disturbance of the gravel and/or substrate during water changes and vacuuming. One routine I use is to vacuum when I change the water. Let the filter take out the bigger "chunks", and the following day clean the filter media. This will likely clear up the water faster. A 30% water change on a 65 is not likely to cause a mini-cycle on a 2 year old tank unless the parameters are screwed up to begin with.